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Article

Interleukin-1 as a genetic marker for periodontitis: review of the literature.

Quintessence international (Berlin, Germany : 1985) - 1 Jun 2010

Grigoriadou Marianna E, Koutayas Spiridon-Oumvertos, Madianos Phoebus N, Strub Jorg-Rudolf

Abstract excerpt

Periodontitis is considered to be a multifactorial disease. Studies have indicated that part of the clinical variability in periodontitis may be explained by genetic factors. Genes can affect the immunoinflammatory host response to bacterial challenge in the periodontal tissues by means of an overproduction of proinflammatory cytokines, such as interleukin-1 (IL-1). IL-1 plays an important role in the...

Topics

Aggressive Periodontitis
Chronic Periodontitis
Disease Progression
Genetic Markers
Genetic Predisposition to Disease
Genetic Variation
Genotype
Humans
Interleukin-1
Periodontitis
Polymorphism, Genetic

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PMID: 20490394

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