Article
Gene polymorphisms of TNF-α and IL-1β are not associated with generalized aggressive periodontitis in an Iranian subpopulation.
Iranian journal of allergy, asthma, and immunology - 28 Aug 2013
Ebadian Ahmad Reza, Radvar Mehrdad, Tavakkol Afshari Jalil, Sargolzaee Naser, Brook Azam, Ganjali Rashiin, Tamizi Mahmood, Arab Hamid Reza
Abstract excerpt
Cytokines play a part in pathogenesis of periodontitis via inflammation phenomenon. Aggressive periodontitis (AgP) is a multifactorial disease resulting in rapid tooth loss due to severe destruction of tooth supporting apparatus. Recently, researchers have focused on genetic susceptibility of periodontitis through investigating the gene variations of cytokines and other components of immune response. In this...
Topics
- Adolescent
- Adult
- Aggressive Periodontitis
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Humans
- Interleukin-1beta
- Male
- Polymorphism, Single Nucleotide