Article
[Interleukin-1 polymorphisms in patients with aggressive periodontitis].
Shanghai kou qiang yi xue = Shanghai journal of stomatology - 1 Aug 2005
Li Qi-yan, Zhao Hong-shan, Meng Huan-xin, Zhang Li, Xu Li, Chen Zhi-bin
Abstract excerpt
PURPOSE: To study whether interleukin-1 (IL-1) genotypes and/or alleles were associated with aggressive periodontitis (AgP). METHODS: Anti-coagulated peripheral blood samples were obtained from 122 AgP patients and 95 healthy controls. Genomic DNA was extracted from each sample. Single nucleotide polymorphisms (SNPs) at IL-1A +4845 and IL-1B +3954 were analyzed by standard polymerase chain reaction-restriction...
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