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Article

Interleukin-1 receptor gene variants are associated with aggressive periodontitis in the Japanese.

Archives of oral biology - 1 Jul 2014

Kamei Hidehiko, Ishihara Yuichi, Fuma Daisuke, Niwa Takafumi, Kamiya Yosuke, Yokoi Takamasa, Suzuki Mariyo, Izawa Ario, Mizutani Hiroki, Hayashi Jun-Ichiro, Sakaki Yoshiyuki, Noguchi Toshihide, Kojima Toshio

Abstract excerpt

OBJECTIVE: Previous studies have indicated that type-1 and type-2 interleukin-1 (IL-1) receptors (IL-1R1 and IL-1R2) play important roles in periodontitis progression. We investigated the association between periodontitis and polymorphisms in the IL-1R1 and IL-1R2 genes (IL1R1 and IL1R2). DESIGN: We searched for genetic variants in IL1R1 and IL1R2 in 24 Japanese patients with aggressive periodontitis (AgP) and 24...

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PMID: 24818754
DOI: 10.1016/j.archoralbio.2014.04.006

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