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Article

Analysis of -1082 IL-10 gene polymorphism in Iranian patients with generalized aggressive periodontitis.

Medical science monitor : international medical journal of experimental and clinical research - 1 Nov 2007

Mellati Ehsan, Arab Hamid R, Tavakkol-Afshari Jalil, Ebadian Ahmad R, Radvar Mehrdad

Abstract excerpt

BACKGROUND: Periodontitis is a multifactorial disease and its severe forms, such as aggressive periodontitis, are suggested to have a genetic basis. Among the genetic factors, polymorphisms in cytokine genes have recently been described in susceptibility to periodontitis. IL-10 is a multi-functional cytokine thought to play a role in the pathogenesis of periodontitis. A substitution G/A polymorphism in the...

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PMID: 17968299

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