Article
Differential Influence of Normal and Cancer-Associated Fibroblasts on the Growth of Human Epithelial Cells in an <i>In vitro</i> Cocultivation Model of Prostate Cancer
12 Aug 2009
Abstract excerpt
The prostate is composed of a number of different cell populations. The interaction between them is crucial for the development and proper function of the prostate. However, the effect of the molecular cross talk between these cells in the course of carcinogenesis is still unclear. Employing an approach wherein immortalized epithelial cells and immortalized human fibroblasts were cocultured, we show that normal...
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