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Article

CXCL12 overexpression and secretion by aging fibroblasts enhance human prostate epithelial proliferation <i>in vitro</i>

7 Nov 2005

Abstract excerpt

The direct relationship between the aging process and the incidence and prevalence of both benign prostatic hyperplasia (BPH) and prostate cancer (PCa) implies that certain risk factors associated with the development of both diseases increase with the aging process. In particular, both diseases share an overly proliferative phenotype, suggesting that mechanisms that normally act to suppress cellular...

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PMID: 16300481
DOI: 10.1111/j.1474-9726.2005.00173.x

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