Article
Constitutive expression of FGF2/bFGF in non-tumorigenic human prostatic epithelial cells results in the acquisition of a partial neoplastic phenotype.
International journal of cancer - 29 Jul 1997
Ropiquet F, Berthon P, Villette J M, Le Brun G, Maitland N J, Cussenot O, Fiet J
Abstract excerpt
Fibroblast growth factor 2 (FGF2), also known as basic fibroblast growth factor (bFGF), belongs to the FGF family, which consists of at least 9 closely related members. FGF2 is a potent mitogen for fibroblasts derived from normal prostate and, to a lesser extent, for prostatic epithelial cells. I...
Topics
- Animals
- Cell Division
- Cell Line
- DNA, Complementary
- Epithelium
- Fibroblast Growth Factor 2
- Filaggrin Proteins
- Gene Expression
- Humans
- Male
- Mice
- Neoplasm Invasiveness
- Phenotype
- Polymerase Chain Reaction
- Prostate