Article
Treatment with Cannabinoids as a Promising Approach for Impairing Fibroblast Activation and Prostate Cancer Progression.
International journal of molecular sciences - 25 Jan 2020
Pietrovito Laura, Iozzo Marta, Bacci Marina, Giannoni Elisa, Chiarugi Paola
Abstract excerpt
Endo-, phyto- and synthetic cannabinoids have been proposed as promising anti-cancer agents able to impair cancer cells' behavior without affecting their non-transformed counterparts. However, cancer outcome depends not only on cancer cells' activity, but also on the stromal cells, which coevolve with cancer cells to sustain tumor progression. Here, we show for the first time that cannabinoid treatment impairs...
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