Article
Human epithelial cells immortalized by human papilloma viruses.
Critical reviews in oncogenesis - 1 Jan 1995
Zheng J, Vaheri A
Abstract excerpt
Human papillomaviruses (HPVs) are small DNA viruses capable of inducing proliferation of epithelial cells in the natural hosts. The etiologic association between HPV and many forms of human cancer, especially squamous tumors of the anogenital region, has been generally recognized. Human epithelial cells transfected by high-risk-type HPV DNA can overcome apoptosis and become immortalized, but they are not capable...
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