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Article

Drosophila O-GlcNAc transferase (OGT) is encoded by the Polycomb group (PcG) gene, super sex combs (sxc).

Proceedings of the National Academy of Sciences of the United States of America - 11 Aug 2009

Sinclair Donald A R, Syrzycka Monika, Macauley Matthew S, Rastgardani Tara, Komljenovic Ivana, Vocadlo David J, Brock Hugh W, Honda Barry M

Abstract excerpt

O-linked N-acetylglucosamine transferase (OGT) reversibly modifies serine and threonine residues of many intracellular proteins with a single beta-O-linked N-acetylglucosamine residue (O-GlcNAc), and has been implicated in insulin signaling, neurodegenerative disease, cellular stress response, and other important processes in mammals. OGT also glycosylates RNA polymerase II and various transcription factors,...

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Identifiers

PMID: 19666537
DOI: 10.1073/pnas.0904638106
PMCID: PMC2726349

Genes

OGT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Drosophila O-GlcNAc transferase (OGT) is encoded by the Polycomb group (PcG) gene, super sex combs (sxc).PMID 19666537Read ↗

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