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A High Density Map for Navigating the Human Polycomb Complexome

2016-06-28

Abstract excerpt

Polycomb group (PcG) proteins are major determinants of gene silencing and epigenetic memory in higher eukaryotes. Here, we used a robust affinity purification mass spectrometry (AP-MS) approach to systematically map the human PcG protein interactome, uncovering an unprecedented breadth of PcG complexes. The obtained high density protein interaction data identified new modes of combinatorial PcG complex formation...

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Literature Corpus work
908c87f2-6c1d-53d0-81ec-eb2d672fc03a
DOI
10.1101/059964
Open publication

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A High Density Map for Navigating the Human Polycomb ComplexomeDOI 10.1101/059964
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