Article
Phosphorylation of the RNA polymerase II C-terminal domain by TFIIH kinase is not essential for transcription of Saccharomyces cerevisiae genome.
Proceedings of the National Academy of Sciences of the United States of America - 25 Aug 2009
Hong Sun Woo, Hong Seong Min, Yoo Jae Wook, Lee Young Chul, Kim Soyoun, Lis John T, Lee Dong-Ki
Abstract excerpt
Ser-5 phosphorylation of the RNA polymerase II (Pol II) C-terminal domain by TFIIH kinase has been implicated in critical steps in mRNA synthesis, such as Pol II promoter escape and mRNA 5'-capping. However, the general requirement and precise role of TFIIH kinase in Pol II transcription still re...
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