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Article

Functional mineralocorticoid receptor (MR) gene variation influences the cortisol awakening response after dexamethasone.

Psychoneuroendocrinology - 1 Apr 2010

van Leeuwen Nienke, Kumsta Robert, Entringer Sonja, de Kloet E Ronald, Zitman Frans G, DeRijk Roel H, Wüst Stefan

Abstract excerpt

Stress causes activation of the hypothalamic-pituitary-adrenal (HPA) axis and results in the secretion of corticosteroids, which facilitate behavioral adaptation and promote the termination of the stress response. These actions exerted by cortisol are mediated by two brain corticosteroid receptor types: the high affinity mineralocorticoid (MR) and the low affinity glucocorticoid receptor (GR). Dexamethasone is a...

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Identifiers

PMID: 19665310
DOI: 10.1016/j.psyneuen.2009.07.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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