Article
Association of hypothalamic-pituitary-adrenal axis-related polymorphisms with stress in asthmatic children on inhaled corticosteroids.
Neuroimmunomodulation - 1 Jan 2012
Tsartsali Lemonia, Papadopoulos Marios, Lagona Evagelia, Papadimitriou Anastasios, Kanaka-Gantenbein Christina, Louizou Eirini, Kastania Anastasia, Priftis Kostas N, Chrousos George
Abstract excerpt
OBJECTIVE: Long-term treatment of asthmatic children with low and moderate doses of inhaled corticosteroids (ICS) may result in mild adrenal suppression. Various associations have been shown between adrenal reactivity and single nucleotide polymorphisms (SNPs) related to the hypothalamic-pituitary-adrenal (HPA) axis. We aimed to investigate the genetic contribution of four HPA axis-related SNPs to the individual...
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