Article
Potential association of DRD2 and DAT1 genetic variation with heroin dependence.
Neuroscience letters - 23 Oct 2009
Hou Qiao-Fang, Li Sheng-Bin
Abstract excerpt
The aim of our study was to investigate the potential association of dopamine receptor D2 gene (DRD2) TaqI RFLP A (rs1800497) and dopamine transporter gene (DAT) 3'untranslated region VNTR genetic variations with heroin addiction. Genotyping was performed using PCR-based techniques in 530 heroin abusers and 500 controls. Our results showed that DRD2 TaqI A1 allele carriers (genotypes A1A1 and A1A2) were prone to...
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