Article
Association of Dopamine Transporter Gene with Heroin Dependence in an Indian Subpopulation from Manipur.
Journal of molecular neuroscience : MN - 1 Jan 2021
Koijam Arunkumar Singh, Hijam Aruna Chanu, Singh Asem Surindro, Jaiswal Preeti, Mukhopadhyay Kanchan, Rajamma Usha, Haobam Reena
Abstract excerpt
Dopamine transporter (DAT) or solute carrier family 6 member 3 (SLC6A3) is a transmembrane protein regulating dopaminergic neurotransmission. It has been implicated in playing important roles in the dopaminergic reward pathways, and thus, DAT1 is a strong candidate gene for association studies with heroin dependence. A case-control study involving 279 individuals (147 controls and 132 heroin-dependent cases) was...
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