Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The D(2) dopamine receptor A(1) allele and opioid dependence: association with heroin use and response to methadone treatment.

American journal of medical genetics - 9 Oct 2000

Lawford B R, Young R M, Noble E P, Sargent J, Rowell J, Shadforth S, Zhang X, Ritchie T

Abstract excerpt

A total of 95 Caucasian opioid-dependent patients were followed over a one-year period in an outpatient methadone treatment program. The frequency of the TaqI A(1) allele of the D(2) dopamine receptor (DRD2) gene was 19.0% in these patients compared with 4.6% in controls free of past and current...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Analgesics, Opioid
Share to Analysis of Variance
Share to DNA

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Follow-Up Studies

Share to Gene Frequency

Share to Methadone

Share to Opioid-Related Disorders

Share to Receptors, Dopamine D2

Source

Identifiers

PMID: 11054765
DOI: 10.1002/1096-8628(20001009)96:5<592::aid-ajmg3>3.0.co;2-y

Genes

DRD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11054765-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The D(2) dopamine receptor A(1) allele and opioid dependence: association with heroin use and response to methadone treatment.PMID 11054765Read ↗

Association between the DRD2 A1 allele and response to methadone and buprenorphine maintenance treatments.Semantic proximity Read ↗

Allelic and genotypic associations of DRD2 Taq I A polymorphism with heroin dependence in Spanish subjects: a case control studySemantic proximity Read ↗

The dopamine D2 receptor gene: a genetic risk factor in substance abuse.Semantic proximity Read ↗

Association between dopamine D2 receptor gene polymorphisms and the risk of heroin dependence.Semantic proximity Read ↗

Potential association of DRD2 and DAT1 genetic variation with heroin dependence.Semantic proximity Read ↗

The D2 dopamine receptor gene: a review of association studies in alcoholism and phenotypes.Semantic proximity Read ↗

The aldehyde dehydrogenase 2 gene is associated with heroin dependence.Semantic proximity Read ↗

Addiction and its reward process through polymorphisms of the D2 dopamine receptor gene: a review.Semantic proximity Read ↗

D<sub>2</sub>dopamine receptor (DRD2) polymorphism is associated with severity of alcohol dependenceSemantic proximity Read ↗

Association of specific haplotypes of D2 dopamine receptor gene with vulnerability to heroin dependence in 2 distinct populations.Semantic proximity Read ↗

Advances in molecular genetics and the prevention and treatment of substance misuse: Implications of association studies of the A1 allele of the D2 dopamine receptor gene.Semantic proximity Read ↗

The A1 allele at the D2 dopamine receptor gene and alcoholism. A reappraisal.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.