Article
The dopamine D2 receptor gene: a genetic risk factor in substance abuse.
Drug and alcohol dependence - 1 Feb 1994
Comings D E, Muhleman D, Ahn C, Gysin R, Flanagan S D
Abstract excerpt
Drug abuse has grown to epidemic proportions. Dopaminergic reward pathways have frequently been implicated in the etiology of drug addiction. To examine the possible role of genetic variants of the dopamine D2 (DRD2) gene in susceptibility to drug abuse we determined the prevalence of the TaqI A1 variant of the DRD2 gene in 200 white patients hospitalized in the Addiction Treatment Unit of a Veterans...
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