The dopamine D2 receptor gene: a genetic risk factor in substance abuse.

doi:10.1016/0376-8716(94)90154-6

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Article

The dopamine D2 receptor gene: a genetic risk factor in substance abuse.

Drug and alcohol dependence - 1 Feb 1994

Comings D E, Muhleman D, Ahn C, Gysin R, Flanagan S D

Abstract excerpt

Drug abuse has grown to epidemic proportions. Dopaminergic reward pathways have frequently been implicated in the etiology of drug addiction. To examine the possible role of genetic variants of the dopamine D2 (DRD2) gene in susceptibility to drug abuse we determined the prevalence of the TaqI A1...

Topics

Adult
Aggression
Alcoholism
Alleles
Amphetamines
Cocaine
Deoxyribonucleases, Type II Site-Specific
Female
Genetic Carrier Screening
Humans
Male
Middle Aged
Models, Statistical
Receptors, Dopamine D2
Recurrence
Risk Factors
Substance-Related Disorders
Violence

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