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Large-scale viral genome analysis identifies novel clinical associations between hepatitis B virus and chronically infected patients

19 Jul 2019

Abstract excerpt

Despite the high global prevalence of chronic hepatitis B (CHB) infection, datasets covering the whole hepatitis B viral genome from large patient cohorts are lacking, greatly limiting our understanding of the viral genetic factors involved in this deadly disease. We performed deep sequencing of viral samples from patients chronically infected with HBV to investigate the association between viral genome variation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 31324819
DOI: 10.1038/s41598-019-46609-7

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