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Article

CaV1.3 L-type Ca2+ channels modulate depression-like behaviour in mice independent of deaf phenotype.

The international journal of neuropsychopharmacology - 1 May 2010

Busquet Perrine, Nguyen Ngoc Khoi, Schmid Eduard, Tanimoto Naoyuki, Seeliger Mathias W, Ben-Yosef Tamar, Mizuno Fengxia, Akopian Abram, Striessnig Jörg, Singewald Nicolas

Abstract excerpt

Mounting evidence suggests that voltage-gated L-type Ca2+ channels can modulate affective behaviour. We therefore explored the role of CaV1.3 L-type Ca2+ channels in depression- and anxiety-like behaviours using CaV1.3-deficient mice (CaV1.3-/-). We showed that CaV1.3-/- mice displayed less immob...

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Source

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PMID: 19664321
DOI: 10.1017/S1461145709990368

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19664321-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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