Article
L-type voltage-gated calcium channels in conditioned fear: a genetic and pharmacological analysis.
Learning & memory (Cold Spring Harbor, N.Y.) - 1 May 2008
McKinney Brandon C, Sze Wilson, White Jessica A, Murphy Geoffrey G
Abstract excerpt
Using pharmacological approaches, others have suggested that L-type voltage-gated calcium channels (L-VGCCs) mediate both consolidation and extinction of conditioned fear. In the absence of L-VGCC isoform-specific antagonists, we have begun to investigate the subtype-specific role of LVGCCs in consolidation and extinction of conditioned fear using a molecular genetics approach. Previously, we used this approach...
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