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Article

A single-nucleotide polymorphism in the MDR1 gene as a predictor of response to neoadjuvant chemotherapy in breast cancer.

Clinical breast cancer - 1 Aug 2009

George Joseph, Dharanipragada Kadambari, Krishnamachari Srinivasan, Chandrasekaran Adithan, Sam Soya Sisy, Sunder Elangovan

Abstract excerpt

BACKGROUND: The single-nucleotide polymorphism (SNP) 3435C > T in exon 26 of the MDR1 gene has been shown to correlate with the functioning of P-glycoprotein. We studied the frequency of SNP in exon 26 of the MDR1 gene in breast cancer and its role in predicting response to neoadjuvant chemotherapy in breast cancer. PATIENTS AND METHODS: Ninety-six patients with locally advanced breast carcinoma were enrolled....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19661039
DOI: 10.3816/CBC.2009.n.026

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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