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Article

Central nervous system serotonin function and cardiovascular responses to stress.

Psychosomatic medicine - 1 Jan 2000

Williams R B, Marchuk D A, Gadde K M, Barefoot J C, Grichnik K, Helms M J, Kuhn C M, Lewis J G, Schanberg S M, Stafford-Smith M, Suarez E C, Clary G L, Svenson I K, Siegler I C

Abstract excerpt

OBJECTIVE: The objective of this study was to evaluate the impact of indices of central nervous system (CNS) serotonin function on cardiovascular reactivity to mental stress. METHODS: Lumbar puncture was performed on 54 healthy volunteers to obtain cerebrospinal fluid (CSF) for determination of 5-hydroxyindoleacetic acid (5HIAA) levels. Genotypes were determined with respect to a functional polymorphism of the...

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Identifiers

PMID: 11292279
DOI: 10.1097/00006842-200103000-00016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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