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Article

Improving detection of differentially expressed gene sets by applying cluster enrichment analysis to Gene Ontology.

BMC bioinformatics - 5 Aug 2009

Xu Tao, Gu JianLei, Zhou Yan, Du LinFang

Abstract excerpt

BACKGROUND: Gene set analysis based on Gene Ontology (GO) can be a promising method for the analysis of differential expression patterns. However, current studies that focus on individual GO terms have limited analytical power, because the complex structure of GO introduces strong dependencies among the terms, and some genes that are annotated to a GO term cannot be found by statistically significant enrichment....

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PMID: 19653916
DOI: 10.1186/1471-2105-10-240
PMCID: PMC2731756

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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