Article
A novel method to quantify gene set functional association based on gene ontology.
Journal of the Royal Society, Interface - 7 May 2012
Lv Sali, Li Yan, Wang Qianghu, Ning Shangwei, Huang Teng, Wang Peng, Sun Jie, Zheng Yan, Liu Weisha, Ai Jing, Li Xia
Abstract excerpt
Numerous gene sets have been used as molecular signatures for exploring the genetic basis of complex disorders. These gene sets are distinct but related to each other in many cases; therefore, efforts have been made to compare gene sets for studies such as those evaluating the reproducibility of different experiments. Comparison in terms of biological function has been demonstrated to be helpful to biologists. We...
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