Article
Genetic variations in regulatory pathways of fatty acid and glucose metabolism are associated with obesity phenotypes: a population-based cohort study.
International journal of obesity (2005) - 1 Oct 2009
van den Berg S W, Dollé M E T, Imholz S, van der A D L, van 't Slot R, Wijmenga C, Verschuren W M M, Strien C, Siezen C L E, Hoebee B, Feskens E J M, Boer J M A
Abstract excerpt
BACKGROUND: As nuclear receptors and transcription factors have an important regulatory function in adipocyte differentiation and fat storage, genetic variation in these key regulators and downstream pathways may be involved in the onset of obesity. OBJECTIVE: To explore associations between single nucleotide polymorphisms (SNPs) in candidate genes from regulatory pathways that control fatty acid and glucose...
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