Article
Association studies of novel obesity-related gene variants with quantitative metabolic phenotypes in a population-based sample of 6,039 Danish individuals.
Diabetologia - 1 Jan 2012
Burgdorf K S, Gjesing A P, Grarup N, Justesen J M, Sandholt C H, Witte D R, Jørgensen T, Madsbad S, Hansen T, Pedersen O
Abstract excerpt
AIMS/HYPOTHESIS: Genome-wide association studies have identified novel WHR and BMI susceptibility loci. The aim of this study was to elucidate if any of these loci had an effect on quantitative measures of glucose homeostasis, including estimates of insulin release and insulin sensitivity in an epidemiological setting. METHODS: By applying an additive genetic model, 14 WHR-associated gene variants and 18...
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