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PNPLA3 rs738409 underlies treatment response in nonalcoholic fatty liver disease

16 Aug 2018

Abstract excerpt

Non-alcoholic fatty liver disease (NAFLD) has now become the leading cause of chronic liver disease with its growing incidence worldwide. Patatin-like phospholipase domain-containing protein 3 (PNPLA3) rs738409 C > G reflects one of the critical genetic factors that confers high-risk to NAFLD. However, the role of PNPLA3 polymorphism in NAFLD treatment remains uncertain. Here, the present review reveals that...

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PMID: 30148144
DOI: 10.12998/wjcc.v6.i8.167

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