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Article

A microarray‐based approach for the identification of epigenetic biomarkers for the noninvasive diagnosis of fetal disease

31 Jul 2009

Abstract excerpt

OBJECTIVES: We describe a novel microarray-based approach for the high-throughput discovery of epigenetic biomarkers for use in the noninvasive detection of fetal genetic disease. METHODS: We combined a 215 060-probe custom oligonucleotide microarray with a comprehensive library preparation method and novel statistical tools to compare DNA methylation patterns in chorionic villus samples (CVS) with gestational...

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Share to Fetal and Pediatric Neurological Disorders
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Share to Prenatal Screening and Diagnostics

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PMID: 19650061
DOI: 10.1002/pd.2335

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