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Exploration of cfDNA landscape in NIPT and clinical utilities of cfDNA based gene expression inference in prenatal diagnostics

21 Feb 2025

Abstract excerpt

Cell-free DNA (cfDNA) is a dynamic biomarker reflecting the physiological state of the body. Its unique physical and biochemical properties, inherited from the tissue of origin, enable a wide range of clinical applications. From methylation patterns and fragmentation profiles to genetic variants, cfDNA holds immense potential for diagnosing and monitoring various diseases, including cancer. In this study, we...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40061129
DOI: 10.3389/fgene.2025.1527884

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