Article
Advancing diagnosis and early risk assessment of preeclampsia through noninvasive cell-free DNA methylation profiling
18 Dec 2024
Abstract excerpt
BACKGROUND: Aberrant embryo implantation and suboptimal placentation can lead to (severe) complications such as preeclampsia and fetal growth restriction later in pregnancy. Current identification of high-risk pregnancies relies on a combination of risk factors, biomarkers, and ultrasound examinations, a relatively inaccurate approach. Previously, aberrant DNA methylation due to placental hypoxia has been...
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