Article
Epigenome-wide DNA methylation assay reveals placental epigenetic markers for noninvasive fetal single-nucleotide polymorphism genotyping in maternal plasma.
Transfusion - 1 Oct 2014
Ou Xueling, Wang Huan, Qu Dongyang, Chen Yongzhen, Gao Jun, Sun Hongyu
Abstract excerpt
BACKGROUND: The use of DNA methylation difference between maternal blood cell and fetal (placental) DNA is one of the main areas of interest for the development of fetal epigenetics markers in maternal plasma. STUDY DESIGN AND METHODS: We employed a methylation array (HumanMethylation450 array, I...
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