Article
Facilitation of autonomous phenotype acquisition in androgen-dependent Shionogi carcinoma 115 cells by transfection of androgen-induced growth factor expression vector.
Japanese journal of cancer research : Gann - 1 Nov 1994
Miyashita Y, Koga M, Kouhara H, Tanaka A, Kishimoto T, Sato B
Abstract excerpt
Androgen-induced growth factor (AIGF) is an autocrine growth factor for androgen-dependent SC-3 cells, which is induced by androgen stimuli. To elucidate the mechanism of the progression from hormone-dependent to -independent tumor, we transfected an expression vector of cDNA encoding AIGF into S...
Topics
- Androgens
- Animals
- Base Sequence
- Cell Division
- DNA
- Fibroblast Growth Factor 2
- Growth Substances
- Mammary Neoplasms, Experimental
- Mice
- Molecular Sequence Data
- Neoplasms, Hormone-Dependent
- Phenotype
- Transfection