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Article

Facilitation of autonomous phenotype acquisition in androgen-dependent Shionogi carcinoma 115 cells by transfection of androgen-induced growth factor expression vector.

Japanese journal of cancer research : Gann - 1 Nov 1994

Miyashita Y, Koga M, Kouhara H, Tanaka A, Kishimoto T, Sato B

Abstract excerpt

Androgen-induced growth factor (AIGF) is an autocrine growth factor for androgen-dependent SC-3 cells, which is induced by androgen stimuli. To elucidate the mechanism of the progression from hormone-dependent to -independent tumor, we transfected an expression vector of cDNA encoding AIGF into SC-3 cells and established a stable transfectant (A1) expressing AIGF. A1 cells showed enhanced DNA synthesis. This...

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Identifiers

PMID: 7829396
DOI: 10.1111/j.1349-7006.1994.tb02916.x
PMCID: PMC5919376

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Source receipt: pubmed, retrieved 7 Sept 2026.

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