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Article

Comprehensive resequence analysis of a 97 kb region of chromosome 10q11.2 containing the MSMB gene associated with prostate cancer.

Human genetics - 1 Dec 2009

Yeager Meredith, Deng Zuoming, Boland Joseph, Matthews Casey, Bacior Jennifer, Lonsberry Victor, Hutchinson Amy, Burdett Laura A, Qi Liqun, Jacobs Kevin B, Gonzalez-Bosquet Jesus, Berndt Sonja I, Hayes Richard B, Hoover Robert N, Thomas Gilles, Hunter David J, Dean Michael, Chanock Stephen J

Abstract excerpt

Genome-wide association studies of prostate cancer have identified single nucleotide polymorphism (SNP) markers in a region of chromosome 10q11.2, harboring the microseminoprotein-β (MSMB) gene. Both the gene product of MSMB, the prostate secretory protein 94 (PSP94) and its binding protein (PSPBP), have been previously investigated as serum biomarkers for prostate cancer progression. Recent functional work has...

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Share to Chromosomes, Human, Pair 10
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Linkage Disequilibrium

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Source

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Identifiers

PMID: 19644707
DOI: 10.1007/s00439-009-0723-9
PMCID: PMC2778717

Genes

MSMB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comprehensive resequence analysis of a 97 kb region of chromosome 10q11.2 containing the MSMB gene associated with prostate cancer.PMID 19644707Read ↗

Fine mapping and functional analysis of a common variant in MSMB on chromosome 10q11.2 associated with prostate cancer susceptibility.Semantic proximity Read ↗

Fine mapping association study and functional analysis implicate a SNP in MSMB at 10q11 as a causal variant for prostate cancer risk.Semantic proximity Read ↗

The rs10993994 risk allele for prostate cancer results in clinically relevant changes in microseminoprotein-beta expression in tissue and urine.Semantic proximity Read ↗

Microseminoprotein-Beta Expression in Different Stages of Prostate Cancer.Semantic proximity Read ↗

Investigation of the relationship between prostate cancer and MSMB and NCOA4 genetic variants and protein expression.Semantic proximity Read ↗

The potential value of microseminoprotein-beta as a prostate cancer biomarker and therapeutic target.Semantic proximity Read ↗

Mutation analysis of the MSMB gene in familial prostate cancer.Semantic proximity Read ↗

Validation of prostate cancer risk variants rs10993994 and rs7098889 by CRISPR/Cas9 mediated genome editing.Semantic proximity Read ↗

MSMB gene rs10993994 polymorphism increases the risk of prostate cancer.Semantic proximity Read ↗

A common prostate cancer risk variant 5' of microseminoprotein-beta (MSMB) is a strong predictor of circulating beta-microseminoprotein (MSP) levels in multiple populations.Semantic proximity Read ↗

Polymorphisms at the Microseminoprotein-beta locus associated with physiologic variation in beta-microseminoprotein and prostate-specific antigen levels.Semantic proximity Read ↗

Validation of prostate cancer risk variants by CRISPR/Cas9 mediated genome editingSemantic proximity Read ↗

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