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Article

The potential value of microseminoprotein-beta as a prostate cancer biomarker and therapeutic target.

The Prostate - 15 Feb 2010

Whitaker Hayley C, Warren Anne Y, Eeles Rosalind, Kote-Jarai Zsofia, Neal David E

Abstract excerpt

BACKGROUND: Recent genome-wide association studies have shown an association of a SNP two base pairs upstream of the 5' UTR of the microseminoprotein-beta (MSMB) gene with an increased risk of developing the prostate cancer, re-igniting interest in its protein product, MSMB. METHODS: As one of th...

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Source

Identifiers

PMID: 19790236
DOI: 10.1002/pros.21059

Genes

MSMB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19790236-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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The potential value of microseminoprotein-beta as a prostate cancer biomarker and therapeutic target.PMID 19790236Read ↗

Microseminoprotein-Beta Expression in Different Stages of Prostate Cancer.Semantic proximity Read ↗

The rs10993994 risk allele for prostate cancer results in clinically relevant changes in microseminoprotein-beta expression in tissue and urine.Semantic proximity Read ↗

Comprehensive resequence analysis of a 97 kb region of chromosome 10q11.2 containing the MSMB gene associated with prostate cancer.Semantic proximity Read ↗

A common prostate cancer risk variant 5' of microseminoprotein-beta (MSMB) is a strong predictor of circulating beta-microseminoprotein (MSP) levels in multiple populations.Semantic proximity Read ↗

Polymorphisms at the Microseminoprotein-beta locus associated with physiologic variation in beta-microseminoprotein and prostate-specific antigen levels.Semantic proximity Read ↗

Mutation analysis of the MSMB gene in familial prostate cancer.Semantic proximity Read ↗

Fine mapping and functional analysis of a common variant in MSMB on chromosome 10q11.2 associated with prostate cancer susceptibility.Semantic proximity Read ↗

Effect of androgen deprivation therapy on the expression of prostate cancer biomarkers MSMB and MSMB-binding protein CRISP3.Semantic proximity Read ↗

MSMB gene rs10993994 polymorphism increases the risk of prostate cancer.Semantic proximity Read ↗

Rapidly evolving marmoset MSMB genes are differently expressed in the male genital tract.Semantic proximity Read ↗

Analysis of the Human Prostate-Specific Proteome Defined by Transcriptomics and Antibody-Based Profiling Identifies TMEM79 and ACOXL as Two Putative, Diagnostic Markers in Prostate CancerSemantic proximity Read ↗

Validation of prostate cancer risk variants rs10993994 and rs7098889 by CRISPR/Cas9 mediated genome editing.Semantic proximity Read ↗

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