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Article

MSMB gene rs10993994 polymorphism increases the risk of prostate cancer.

Oncotarget - 25 Apr 2017

Peng Tao, Zhang Lifeng, Zhu Lijie, Mi Yuan-Yuan

Abstract excerpt

Genome-wide association studies (GWASs) identified microseminoprotein-β (MSMB) gene rs10993994 polymorphism was significantly associated with prostate cancer (PC) risk. However, the association between MSMB gene rs10993994 polymorphism and PC risk remains controversial. Therefore, we performed a systematic review and meta-analysis by searching in the databases of PubMed, and Embase. Pooled odds ratios (ORs) and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28212531
DOI: 10.18632/oncotarget.15312
PMCID: PMC5438667

Genes

MSMB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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MSMB gene rs10993994 polymorphism increases the risk of prostate cancer.PMID 28212531Read ↗

A meta-analysis of influence of MSMB promoter rs10993994 polymorphisms on prostate cancer risk.Semantic proximity Read ↗

Investigation of the relationship between prostate cancer and MSMB and NCOA4 genetic variants and protein expression.Semantic proximity Read ↗

Fine mapping and functional analysis of a common variant in MSMB on chromosome 10q11.2 associated with prostate cancer susceptibility.Semantic proximity Read ↗

A common prostate cancer risk variant 5' of microseminoprotein-beta (MSMB) is a strong predictor of circulating beta-microseminoprotein (MSP) levels in multiple populations.Semantic proximity Read ↗

The rs10993994 risk allele for prostate cancer results in clinically relevant changes in microseminoprotein-beta expression in tissue and urine.Semantic proximity Read ↗

A functional polymorphism in MSMB gene promoter is associated with prostate cancer risk and serum MSMB expression.Semantic proximity Read ↗

Microseminoprotein-Beta Expression in Different Stages of Prostate Cancer.Semantic proximity Read ↗

Comprehensive resequence analysis of a 97 kb region of chromosome 10q11.2 containing the MSMB gene associated with prostate cancer.Semantic proximity Read ↗

Association of prostate cancer susceptibility variant (MSMB) rs10993994 with risk of spermatogenic failure.Semantic proximity Read ↗

Polymorphisms at the Microseminoprotein-beta locus associated with physiologic variation in beta-microseminoprotein and prostate-specific antigen levels.Semantic proximity Read ↗

MSMB gene variant alters the association between prostate cancer and number of sexual partners.Semantic proximity Read ↗

The potential value of microseminoprotein-beta as a prostate cancer biomarker and therapeutic target.Semantic proximity Read ↗

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