Article
PIP5K2A-dependent regulation of excitatory amino acid transporter EAAT3.
Psychopharmacology - 1 Oct 2009
Fedorenko Olga, Tang Cai, Sopjani Mentor, Föller Michael, Gehring Eva-Maria, Strutz-Seebohm Nathalie, Ureche Oana N, Ivanova Svetlana, Semke Arkadij, Lang Florian, Seebohm Guiscard, Lang Undine E
Abstract excerpt
INTRODUCTION: According to previous observations, the gene encoding the phosphatidylinositol-4-phosphate 5-kinase II alpha (PIP5K2A) is associated with schizophrenia. Specifically, the mutation (N251S)PIP5K2A has been discovered in schizophrenic patients but not in healthy individuals. A defect o...
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