Article
Sequential activation of protein kinase C isoforms by organic dust is mediated by tumor necrosis factor.
American journal of respiratory cell and molecular biology - 1 Jun 2010
Wyatt Todd A, Slager Rebecca E, Heires Arthur J, Devasure Jane M, Vonessen Susanna G, Poole Jill A, Romberger Debra J
Abstract excerpt
Dust samples collected from Nebraska swine confinement facilities (hog dust extract [HDE]) are known to elicit proinflammatory cytokine release from human bronchial epithelial (HBE) cells in vitro. This response involves the activation of two protein kinase C (PKC) isoforms: PKCalpha and PKCepsil...
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