Article
Increased cytochrome P4501B1 gene expression in peripheral leukocytes of municipal waste incinerator workers.
Toxicology letters - 5 Jan 2006
Hu Suh-Woan, Chen Chun-Chieh, Kuo Chung-Yih, Lin Wen-Hai, Lin Pinpin
Abstract excerpt
Incinerator workers are exposed to polycyclic aromatic hydrocarbons (PAHs) and dioxins in workplace. Previous studies indicated that aryl hydrocarbon receptor activation, following by increased cytochrome P4501A1 (CYP1A1) and 1B1 (CYP1B1) activity and expressions, was required for PAHs and dioxin induced toxicities. This study investigated whether municipal waste incinerator workers with frequent exposure to...
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