Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Environmental factors and aryl hydrocarbon hydroxylase activity (CYP1A1 phenotype) in human lymphocytes.

Journal of epidemiology - 1 Dec 1997

Kiyohara C, Hirohata T

Abstract excerpt

Since aryl hydrocarbon hydroxylase (AHH) is considered to be responsible for the activation of benzo(a)pyrene (BP) and other polyaromatic hydrocarbons in cigarette smoke to carcinogens, it is important to examine AHH activity in the determination of susceptibility to lung cancer. Lymphocytes from...

Topics

Adult
Aryl Hydrocarbon Hydroxylases
Carcinogens
Cells, Cultured
Cytochrome P-450 CYP1A1
Enzyme Induction
Humans
Lung Neoplasms
Lymphocytes
Male
Methylcholanthrene
Phenotype
Regression Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Risk Factors

Smoking

Source

Identifiers

PMID: 9465551
DOI: 10.2188/jea.7.244

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9465551-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Environmental factors and aryl hydrocarbon hydroxylase activity (CYP1A1 phenotype) in human lymphocytes.PMID 9465551Read ↗

The relationship between CYP1A1 aryl hydrocarbon hydroxylase activity and lung cancer in a Japanese population.Semantic proximity Read ↗

Correlation between gene expression of aryl hydrocarbon receptor (AhR), hydrocarbon receptor nuclear translocator (Arnt), cytochromes P4501A1 (CYP1A1) and 1B1 (CYP1B1), and inducibility of CYP1A1 and CYP1B1 in human lymphocytes.Semantic proximity Read ↗

Arylhydrocarbonhydroxylase inducibility and smoking habits in patients with laryngeal carcinomas.Semantic proximity Read ↗

Sex differences in risk of lung cancer: Expression of genes in the PAH bioactivation pathway in relation to smoking and bulky DNA adducts.Semantic proximity Read ↗

Role of aryl hydrocarbon receptor-mediated induction of the CYP1 enzymes in environmental toxicity and cancer.Semantic proximity Read ↗

Association of polycyclic aromatic hydrocarbons in housewives' hair with hypertension.Semantic proximity Read ↗

Evidence for increased cytochrome P450 1A1 expression in blood lymphocytes of lung cancer patients.Semantic proximity Read ↗

[A role of aryl hydrocarbon hydroxylase inducibility in susceptibility to lung carcinogenesis].Semantic proximity Read ↗

Increased cytochrome P450 and aryl hydrocarbon receptor in bronchial epithelium of heavy smokers with non-small cell lung carcinoma carries a poor prognosis.Semantic proximity Read ↗

The relationship between aryl hydrocarbon hydroxylase and polymorphisms of the CYP1A1 gene.Semantic proximity Read ↗

Airborne polycyclic aromatic hydrocarbons trigger human skin cells aging through aryl hydrocarbon receptorSemantic proximity Read ↗

The Effects of Everyday-life Exposure to Polycyclic Aromatic Hydrocarbons on Biological Age IndicatorsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.