Article
Association between CYP1A1 genotype, mRNA expression and enzymatic activity in humans.
Pharmacogenetics - 1 Oct 1994
Landi M T, Bertazzi P A, Shields P G, Clark G, Lucier G W, Garte S J, Cosma G, Caporaso N E
Abstract excerpt
Genetic susceptibility factors may play a role in determining adverse effects of exposure to environmental toxins. As a preliminary step to a molecular epidemiological study in a population exposed to 2,3,7,8-tetrachlorodibenzo-para-dioxin (TCDD), we investigated 20 healthy Caucasian volunteers with a set of putative susceptibility markers including a CYP1A1 Msp I restriction fragment length genetic polymorphism...
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