Article
Polymorphisms of drug-metabolizing enzymes CYP1A1, GSTT and GSTP contribute to the development of diffuse large B-cell lymphoma risk in the Saudi Arabian population.
Leukemia & lymphoma - 1 Jan 2008
Al-Dayel Fouad, Al-Rasheed Maha, Ibrahim Muna, Bu Rong, Bavi Prashant, Abubaker Jehad, Al-Jomah Naif, Mohamed Gamal H, Moorji Azadali, Uddin Shahab, Siraj Abdul K, Al-Kuraya Khawla
Abstract excerpt
The last four decades have seen significant increase in the incidence of non-Hodgkin lymphoma (NHL) as a possible result of increasing environmental carcinogens exposure. Based on the increasing evidence for the association between carcinogen-exposure-related cancer risk and xenobiotic gene polymorphisms, we have undertaken a hospital based case-control study on xenobiotic gene polymorphisms in Saudi individuals...
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