Article
Comparison of different haplotype-based association methods for gene-environment (GxE) interactions in case-control studies when haplotype-phase is ambiguous.
Human heredity - 1 Jan 2009
Hein Rebecca, Beckmann Lars, Chang-Claude Jenny
Abstract excerpt
OBJECTIVE: We compared four haplotype-based approaches for the analysis of gene-environment interactions when haplotype-phase is ambiguous. The methods employ different versions of the expectation maximization algorithm and differ in the choice of the reference group and in the way the risk of di...
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