Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Retrospective analysis of haplotype-based case control studies under a flexible model for gene environment association.

Biostatistics (Oxford, England) - 1 Jan 2008

Chen Yi-Hau, Chatterjee Nilanjan, Carroll Raymond J

Abstract excerpt

Genetic epidemiologic studies often involve investigation of the association of a disease with a genomic region in terms of the underlying haplotypes, that is the combination of alleles at multiple loci along homologous chromosomes. In this article, we consider the problem of estimating haplotype-environment interactions from case-control studies when some of the environmental exposures themselves may be...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenoma
Share to Arylamine N-Acetyltransferase
Share to Colorectal Neoplasms

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Computer Simulation

Share to Environmental Exposure

Share to Haplotypes

Share to Logistic Models

Share to Models, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 17490987
DOI: 10.1093/biostatistics/kxm011
PMCID: PMC2683243

Genes

NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Retrospective analysis of haplotype-based case control studies under a flexible model for gene environment association.PMID 17490987Read ↗

Haplotype-based association analysis in cohort and nested case-control studies.Semantic proximity Read ↗

Haplotype-based regression analysis and inference of case-control studies with unphased genotypes and measurement errors in environmental exposures.Semantic proximity Read ↗

Efficient semiparametric estimation of haplotype-disease associations in case-cohort and nested case-control studies.Semantic proximity Read ↗

Conditional likelihood methods for haplotype-based association analysis using matched case-control data.Semantic proximity Read ↗

Powerful multilocus tests of genetic association in the presence of gene-gene and gene-environment interactions.Semantic proximity Read ↗

A method for the assessment of disease associations with single-nucleotide polymorphism haplotypes and environmental variables in case-control studies.Semantic proximity Read ↗

Semiparametric odds ratio model for case-control and matched case-control designs.Semantic proximity Read ↗

Analysis of case-control studies of genetic and environmental factors with missing genetic information and haplotype-phase ambiguity.Semantic proximity Read ↗

Testing haplotype-environment interactions using case-parent triads.Semantic proximity Read ↗

Statistical analysis for haplotype-based matched case-control studies.Semantic proximity Read ↗

Maximum likelihood estimation of haplotype effects and haplotype-environment interactions in association studies.Semantic proximity Read ↗

Genotype-based association mapping of complex diseases: gene-environment interactions with multiple genetic markers and measurement error in environmental exposures.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.