Article
Analysis of case-control studies of genetic and environmental factors with missing genetic information and haplotype-phase ambiguity.
Genetic epidemiology - 1 Sept 2005
Spinka Christine, Carroll Raymond J, Chatterjee Nilanjan
Abstract excerpt
Case-control studies of unrelated subjects are now widely used to study the role of genetic susceptibility and gene-environment interactions in the etiology of complex diseases. Exploiting an assumption of gene-environment independence, and treating the distribution of environmental exposures as completely nonparametric, Chatterjee and Carroll recently developed an efficient retrospective maximum-likelihood...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
