Article
Estimation and tests of haplotype-environment interaction when linkage phase is ambiguous.
Human heredity - 1 Jan 2003
Lake S L, Lyon H, Tantisira K, Silverman E K, Weiss S T, Laird N M, Schaid D J
Abstract excerpt
In the study of complex traits, the utility of linkage analysis and single marker association tests can be limited for researchers attempting to elucidate the complex interplay between a gene and environmental covariates. For these purposes, tests of gene-environment interactions are needed. In addition, recent studies have indicated that haplotypes, which are specific combinations of nucleotides on the same...
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