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Article

Analysis of the Par2 modifier of pulmonary adenoma formation in mice.

Experimental lung research - 1 Mar 2005

Wang Min, Wang Yian, You Ming, Devereux Theodora R

Abstract excerpt

Inbred strains of mouse show various susceptibilities to spontaneous and chemical-induced lung tumorigenesis. Genetic analyses have revealed that lung tumor susceptibilities of inbred mouse strains are governed by quantitative trait loci (QLTs) located on multiple chromosomes. A major lung tumor resistance QLT, designated pulmonary adenoma resistance 2 (Par2), was mapped to the mouse chromosome 18 independently...

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Source

Identifiers

PMID: 15828125
DOI: 10.1080/01902140490495598

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Analysis of the Par2 modifier of pulmonary adenoma formation in mice.PMID 15828125Read ↗

Fine mapping and characterization of candidate lung tumor resistance genes for the Par2 locus on mouse chromosome 18.Semantic proximity Read ↗

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Identification of the Par2 (Pulmonary adenoma resistance) locus on mouse chromosome 18, a major genetic determinant for lung carcinogen resistance in BALB/cByJ mice.Semantic proximity Read ↗

Analysis of lung tumorigenesis in chimeric mice indicates the Pulmonary adenoma resistance 2 (Par2) locus to operate in the tumor-initiation stage in a cell-autonomous manner: detection of polymorphisms in the Poli gene as a candidate for Par2.Semantic proximity Read ↗

Identification of Las2, a major modifier gene affecting the Pas1 mouse lung tumor susceptibility locus.Semantic proximity Read ↗

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Fine mapping and identification of candidate pulmonary adenoma susceptibility 1 genes using advanced intercross lines.Semantic proximity Read ↗

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