Analysis of the Par2 modifier of pulmonary adenoma formation in mice.

doi:10.1080/01902140490495598

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Article

Analysis of the Par2 modifier of pulmonary adenoma formation in mice.

Experimental lung research - 1 Mar 2005

Wang Min, Wang Yian, You Ming, Devereux Theodora R

Abstract excerpt

Inbred strains of mouse show various susceptibilities to spontaneous and chemical-induced lung tumorigenesis. Genetic analyses have revealed that lung tumor susceptibilities of inbred mouse strains are governed by quantitative trait loci (QLTs) located on multiple chromosomes. A major lung tumor resistance QLT, designated pulmonary adenoma resistance 2 (Par2), was mapped to the mouse chromosome 18 independently...

Topics

Adenoma
Amino Acid Sequence
Animals
Chromosome Mapping
Gene Expression
Genetic Predisposition to Disease
Lung Neoplasms
Mice
Molecular Sequence Data
Polymorphism, Genetic
Quantitative Trait Loci

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Open in PubMed

Identifiers

PMID: 15828125
DOI: 10.1080/01902140490495598

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