Article
Evidence for sex-specific associations between variation in acid phosphatase locus 1 (ACP1) and insulin sensitivity in Mexican-Americans.
The Journal of clinical endocrinology and metabolism - 1 Oct 2009
Shu Yu-Hsiang, Hartiala Jaana, Xiang Anny H, Trigo Enrique, Lawrence Jean M, Allayee Hooman, Buchanan Thomas A, Bottini Nunzio, Watanabe Richard M
Abstract excerpt
CONTEXT: Acid phosphatase locus 1 (ACP1) is a low molecular weight tyrosine phosphatase that has been shown to be an important regulator of insulin receptor signaling. OBJECTIVE: We tested whether variation in ACP1 is associated with type 2 diabetes-related traits in 1035 individuals in 339 Mexican-American families of probands with or without a previous diagnosis of gestational diabetes mellitus (GDM). DESIGN:...
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