Article
Essential requirement for two-pore channel 1 in NAADP-mediated calcium signaling.
The Journal of cell biology - 27 Jul 2009
Brailoiu Eugen, Churamani Dev, Cai Xinjiang, Schrlau Michael G, Brailoiu G Cristina, Gao Xin, Hooper Robert, Boulware Michael J, Dun Nae J, Marchant Jonathan S, Patel Sandip
Abstract excerpt
Nicotinic acid adenine dinucleotide phosphate (NAADP) is a widespread and potent calcium-mobilizing messenger that is highly unusual in activating calcium channels located on acidic stores. However, the molecular identity of the target protein is unclear. In this study, we show that the previousl...
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